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THX Episode 27 - THX Case Study: Cancer Research — Build & Hand Off with Accountability
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THX Episode 27 - THX Case Study: Cancer Research — Build & Hand Off with Accountability

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🧭 Overview

Cancer is a universal fear—and a multi-billion-dollar industry. This THX case study examines what role government should play in funding cancer research, when private enterprise should take over, and how we ensure the public actually benefits from its investment.

Using the THX frameworks, we explore the tension between innovation and equity, risk and reward, breakthrough and affordability.


✍️ Key Topics Covered

  • The role of the NIH, NCI, and public funding in cancer breakthroughs

  • Private sector innovation—and the pricing controversies it creates

  • A utility-by-utility breakdown of what each sector does best (and worst)

  • A proposal: Build and Hand Off—with accountability


🧠 Who This Is For

  • Health policy makers and public officials

  • Patients, families, and caregivers invested in cancer treatment access

  • Researchers, medtech entrepreneurs, and pharma insiders

  • Citizens who believe public investments should generate public good


🧾 Notable Facts & Stories

  • NIH invested over $7B in cancer research in 2023

  • CAR-T cell therapy, the Cancer Genome Atlas, and mRNA vaccines began with public funding

  • Drugs like Provenge and Imbruvica triggered pricing backlash despite NIH-supported origins


💬 Reflection Prompt

Should a drug developed with taxpayer dollars be priced out of reach for those same taxpayers?
What’s the cost of discovery—and who pays for it in the end?

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